A small fluorophore reporter of protein conformation and redox state.
نویسندگان
چکیده
A new thiol-specific reagent introduces a small bis(methylamino)terephthalic acid fluorophore into proteins. The noninvasive probe with distinct spectroscopic properties offers many advantages for protein labeling, purification, and mechanistic work promising to serve as a powerful tool in studies of protein folding and heme redox reactions.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 20 شماره
صفحات -
تاریخ انتشار 2011